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Calcitonin's therapeutic action in bone and calcium disorders includes which of the following?

Inhibits osteoclast-mediated bone resorption, lowering serum calcium, and providing analgesic effects in vertebral fractures

Calcitonin’s therapeutic action targets bone resorption. It inhibits osteoclast-mediated bone breakdown, which reduces the release of calcium from bone into the bloodstream. As a result, serum calcium levels fall, making calcitonin useful in conditions of hypercalcemia and in helping slow bone loss in osteoporosis. In vertebral fractures, calcitonin can also provide analgesic effects, likely through mechanisms beyond simply lowering calcium, such as modulation of pain pathways. The opposite actions—stimulating osteoclasts, raising serum calcium, or increasing bone resorption—do not describe its therapeutic effect, so those choices are not correct.

Stimulates osteoclast activity

Raises serum calcium

Increases bone resorption

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